Best open nightclubs SoMa San Francisco on Saturday night (US) near you

DNA Lounge is most popular around 11 PM on Saturdays. Visitors usually stay up to 4 hours here. It's most quiet on Mondays.

DNA Lounge has been one of San Francisco's most popular nightclubs for over thirty years, hosting an always-eclectic variety of events, including all-ages live music, 18+ dance parties, burlesque shows, lecture series and private parties.

For more info visit the website or checkout Google Maps.

Visitors usually stay up to 3 hours here.

Dive into San Francisco's unrivaled nightlife at Temple Nightclub, where world-class talent and cutting-edge technology converge for a transcendent experience. Our state-of-the-art Void sound system and mesmerizing 4K LED visuals set the gold standard. Whether in our seven elite VIP booths or the intimate depths of LVL 55 with its exclusive tables, you're destined for an unparalleled night.

For more info visit the website or checkout Google Maps.

Visitors usually stay up to 3 hours here.

For more info visit the website or checkout Google Maps.

Visitors usually stay up to 3 hours here.

Weekdays - Happy Hours with drink specials and more. Weekends: 21+ over only. It's no secret, San Francisco likes a good cocktail & great music.

For more info visit the website or checkout Google Maps.

1015 Folsom is most popular around 11 PM on Saturdays. Visitors usually stay up to 4 hours here. It's most quiet on Thursdays.

San Francisco's award-winning & largest capacity 21+ nightclub with 3x levels features a distinct, multi-room nightlife experience that plays host to many of the world's genre-defining musicians & personalities ranging from LCD Soundsystem to Dave Chappelle to Virgil Abloh to Maceo Plex.

For more info visit the website or checkout Google Maps.

Visitors usually stay up to 3 hours here.

Longest operating South of Market LGBTQ+ leather bar, and registered historical landmark, for its support of the local leather, BDSM and kink communities of San Francisco. The SF Eagle is open for business, during regular, winter-adjusted hours. Visit us online (link provided) for a schedule of our seasonal lineup.

For more info visit the website or checkout Google Maps.